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Oxidation inhibits autophagy protein deconjugation from phagosomes to sustain MHC class II restricted antigen presentation

LC3-associated phagocytosis (LAP) contributes to a wide range of cellular processes and notably to immunity. The stabilization of phagosomes by the macroautophagy machinery in human macrophages can maintain antigen presentation on MHC class II molecules. However, the molecular mechanisms involved in...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Ligeon, Laure-Anne, Pena-Francesch, Maria, Vanoaica, Liliana Danusia, Núñez, Nicolás Gonzalo, Talwar, Deepti, Dick, Tobias P., Münz, Christian
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940406/
https://ncbi.nlm.nih.gov/pubmed/33686057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21829-6
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