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Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing
Antigen preservation for presentation is a hallmark of potent antigen-presenting cells. In this paper, we report that in human macrophages and dendritic cells, a subset of phagosomes gets coated with Atg8/LC3, a component of the molecular machinery of macroautophagy, and maintains phagocytosed antig...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857489/ https://ncbi.nlm.nih.gov/pubmed/24322427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201308173 |
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