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CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer’s disease

Tau is a microtubule associated protein in the brain that aggregates in Alzheimer’s disease to form pathological tangles and neurites. Insoluble tau aggregates composed of the microtubule binding region (MTBR) of tau are highly associated with the cognitive and clinical symptoms of Alzheimer’s disea...

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Dades bibliogràfiques
Publicat a:Brain
Autors principals: Horie, Kanta, Barthélemy, Nicolas R, Sato, Chihiro, Bateman, Randall J
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940175/
https://ncbi.nlm.nih.gov/pubmed/33283854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awaa373
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