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CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer’s disease

Tau is a microtubule associated protein in the brain that aggregates in Alzheimer’s disease to form pathological tangles and neurites. Insoluble tau aggregates composed of the microtubule binding region (MTBR) of tau are highly associated with the cognitive and clinical symptoms of Alzheimer’s disea...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Horie, Kanta, Barthélemy, Nicolas R, Sato, Chihiro, Bateman, Randall J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940175/
https://ncbi.nlm.nih.gov/pubmed/33283854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awaa373
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