Stress-induced nuclear condensation of NELF drives transcriptional downregulation

In response to stress, human cells coordinately downregulate transcription and translation of housekeeping genes. To downregulate transcription, the negative elongation factor (NELF) is recruited to gene promoters impairing RNA polymerase II elongation. Here we report that NELF rapidly forms nuclear...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Rawat, Prashant, Boehning, Marc, Hummel, Barbara, Aprile-Garcia, Fernando, Pandit, Anwit S., Eisenhardt, Nathalie, Khavaran, Ashkan, Niskanen, Einari, Vos, Seychelle M., Palvimo, Jorma J., Pichler, Andrea, Cramer, Patrick, Sawarkar, Ritwick
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939545/
https://ncbi.nlm.nih.gov/pubmed/33548202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2021.01.016
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados