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Ligand bias in receptor tyrosine kinase signaling

Ligand bias is the ability of ligands to differentially activate certain receptor signaling responses compared with others. It reflects differences in the responses of a receptor to specific ligands and has implications for the development of highly specific therapeutics. Whereas ligand bias has bee...

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Pubblicato in:J Biol Chem
Autori principali: Karl, Kelly, Paul, Michael D., Pasquale, Elena B., Hristova, Kalina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939482/
https://ncbi.nlm.nih.gov/pubmed/33122191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV120.015190
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