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ROLE OF RECEPTOR TYROSINE KINASE TRANSMEMBRANE DOMAINS IN CELL SIGNALING AND HUMAN PATHOLOGIES

Receptor tyrosine kinases (RTKs) conduct biochemical signals via lateral dimerization in thwe plasma membrane, and their transmembrane (TM) domains play an important role in the dimerization process. Here we present two models of RTK-mediated signaling, and we discuss the role of the TM domains with...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Li, Edwin, Hristova, Kalina
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301406/
https://ncbi.nlm.nih.gov/pubmed/16700535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060609y
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