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ROLE OF RECEPTOR TYROSINE KINASE TRANSMEMBRANE DOMAINS IN CELL SIGNALING AND HUMAN PATHOLOGIES
Receptor tyrosine kinases (RTKs) conduct biochemical signals via lateral dimerization in thwe plasma membrane, and their transmembrane (TM) domains play an important role in the dimerization process. Here we present two models of RTK-mediated signaling, and we discuss the role of the TM domains with...
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| Publicado no: | Biochemistry |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301406/ https://ncbi.nlm.nih.gov/pubmed/16700535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060609y |
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