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Structure of FGFR3 transmembrane domain dimer: implications for signaling and human pathologies
Fibroblast growth factor receptor 3 (FGFR3) transduces biochemical signals via lateral dimerization in the plasma membrane, and plays an important role in human development and disease. At least 8 different pathogenic mutations, implicated in cancers and growth disorders, have been identified in FGF...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844157/ https://ncbi.nlm.nih.gov/pubmed/24120763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.08.026 |
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