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Specific inhibition of pathogenic receptor tyrosine kinase activation by its transmembrane domain
The transmembrane (TM) domains of receptor tyrosine kinases (RTKs) are believed to be important players in RTK signal transduction. However, the degree of specificity and promiscuity of RTK TM domain lateral interactions in mammalian membranes has not been assessed in detail in the literature. A tec...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2994959/ https://ncbi.nlm.nih.gov/pubmed/20713021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.08.007 |
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