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Specific inhibition of pathogenic receptor tyrosine kinase activation by its transmembrane domain

The transmembrane (TM) domains of receptor tyrosine kinases (RTKs) are believed to be important players in RTK signal transduction. However, the degree of specificity and promiscuity of RTK TM domain lateral interactions in mammalian membranes has not been assessed in detail in the literature. A tec...

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Autors principals: He, Lijuan, Shobnam, Nadia, Hristova, Kalina
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994959/
https://ncbi.nlm.nih.gov/pubmed/20713021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.08.007
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