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High-throughput selection of transmembrane sequences that enhance receptor tyrosine kinase activation
Dimerization is a critical requirement for the activation of the intracellular kinase domains of receptor tyrosine kinases (RTKs). The single transmembrane (TM) helices of RTKs contribute to dimerization, but the details are not well understood. Work with TM helices in various model systems has reve...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158823/ https://ncbi.nlm.nih.gov/pubmed/21767549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.07.004 |
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