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The biophysical basis of receptor tyrosine kinase ligand functional selectivity: Trk-B case study

Tropomyosin receptor kinase B (Trk-B) belongs to the second largest family of membrane receptors, Receptor Tyrosine Kinases (RTKs). Trk-B is known to interact with three different neurotrophins: Brain-Derived Neurotrophic Factor (BDNF), Neurotrophin-4 (NT-4), and Neurotrophin-3 (NT-3). All three neu...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Ahmed, Fozia, Paul, Michael D., Hristova, Kalina
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173487/
https://ncbi.nlm.nih.gov/pubmed/33094812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200671
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