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Dimerization of the Trk receptors in the plasma membrane: effects of their cognate ligands

Receptor tyrosine kinases (RTKs) are cell surface receptors which control cell growth and differentiation, and play important roles in tumorigenesis. Despite decades of RTK research, the mechanism of RTK activation in response to their ligands is still under debate. Here we investigate the interacti...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Ahmed, Fozia, Hristova, Kalina
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918676/
https://ncbi.nlm.nih.gov/pubmed/30366959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180637
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