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α-Synuclein facilitates endocytosis by elevating the steady-state levels of phosphatidylinositol 4,5-bisphosphate

α-Synuclein (α-Syn) is a protein implicated in the pathogenesis of Parkinson's disease (PD). It is an intrinsically disordered protein that binds acidic phospholipids. Growing evidence supports a role for α-Syn in membrane trafficking, including, mechanisms of endocytosis and exocytosis, althou...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Schechter, Meir, Atias, Merav, Abd Elhadi, Suaad, Davidi, Dana, Gitler, Daniel, Sharon, Ronit
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939461/
https://ncbi.nlm.nih.gov/pubmed/33087443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015319
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