BMP-9 and LDL crosstalk regulates ALK-1 endocytosis and LDL transcytosis in endothelial cells

Bone morphogenetic protein-9 (BMP-9) is a circulating cytokine that is known to play an essential role in the endothelial homeostasis and the binding of BMP-9 to the receptor activin-like kinase 1 (ALK-1) promotes endothelial cell quiescence. Previously, using an unbiased screen, we identified ALK-1...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tao, Bo, Kraehling, Jan R., Ghaffari, Siavash, Ramirez, Cristina M., Lee, Sungwoon, Fowler, Joseph W., Lee, Warren L., Fernandez-Hernando, Carlos, Eichmann, Anne, Sessa, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939458/
https://ncbi.nlm.nih.gov/pubmed/33097593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015680
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