Caveolin-1 regulates atherogenesis by attenuating LDL transcytosis and vascular inflammation independent of endothelial nitric oxide synthase activation

BACKGROUND—: Atherosclerosis is driven by synergistic interactions between pathological biomechanical, inflammatory and lipid metabolic factors. Our previous studies demonstrated that absence of caveolin-1 (Cav1)/caveolae in hyperlipidemic mice strongly inhibits atherosclerosis, which was attributed...

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Bibliografiska uppgifter
I publikationen:Circulation
Huvudupphovsmän: Ramírez, Cristina M., Zhang, Xinbo, Bandyopadhyay, Chirosree, Rotllan, Noemi, Sugiyama, Michael G., Aryal, Binod, Liu, Xinran, He, Shun, Kraehling, Jan R., Ulrich, Victoria, Lin, Chin Sheng, Velazquez, Heino, Lasunción, Miguel A., Li, Guangxin, Suárez, Yajaira, Tellides, George, Swirski, Filip K., Lee, Warren L., Schwartz, Martin A., Sessa, William C., Fernández-Hernando, Carlos
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778687/
https://ncbi.nlm.nih.gov/pubmed/31154825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.038571
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