Murine GFP-Mx1 forms nuclear condensates and associates with cytoplasmic intermediate filaments: Novel antiviral activity against VSV

Type I and III interferons induce expression of the “myxovirus resistance proteins” MxA in human cells and its ortholog Mx1 in murine cells. Human MxA forms cytoplasmic structures, whereas murine Mx1 forms nuclear bodies. Whereas both HuMxA and MuMx1 are antiviral toward influenza A virus (FLUAV) (a...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Sehgal, Pravin B., Yuan, Huijuan, Scott, Mia F., Deng, Yan, Liang, Feng-Xia, Mackiewicz, Andrzej
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2021
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939456/
https://ncbi.nlm.nih.gov/pubmed/33077519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015661
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk