Human Antiviral Protein MxA Forms Novel Metastable Membraneless Cytoplasmic Condensates Exhibiting Rapid Reversible Tonicity-Driven Phase Transitions

Phase-separated biomolecular condensates of proteins and nucleic acids form functional membrane-less organelles (e.g., stress granules and P-bodies) in the mammalian cell cytoplasm and nucleus. In contrast to the long-standing belief that interferon (IFN)-inducible human myxovirus resistance protein...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Davis, Deodate, Yuan, Huijuan, Liang, Feng-Xia, Yang, Yang-Ming, Westley, Jenna, Petzold, Chris, Dancel-Manning, Kristen, Deng, Yan, Sall, Joseph, Sehgal, Pravin B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819928/
https://ncbi.nlm.nih.gov/pubmed/31484749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01014-19
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