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C-tag TNF: a reporter system to study TNF shedding
TNF is a highly pro-inflammatory cytokine that contributes not only to the regulation of immune responses but also to the development of severe inflammatory diseases. TNF is synthesized as a transmembrane protein, which is further matured via proteolytic cleavage by metalloproteases such as ADAM17,...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7939438/ https://ncbi.nlm.nih.gov/pubmed/33082141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015248 |
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