C-tag TNF: a reporter system to study TNF shedding

TNF is a highly pro-inflammatory cytokine that contributes not only to the regulation of immune responses but also to the development of severe inflammatory diseases. TNF is synthesized as a transmembrane protein, which is further matured via proteolytic cleavage by metalloproteases such as ADAM17,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Pinci, Francesca, Gaidt, Moritz M., Jung, Christophe, Kuut, Gunnar, Jackson, Margaret A., Bauernfried, Stefan, Hornung, Veit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2021
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939438/
https://ncbi.nlm.nih.gov/pubmed/33082141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015248
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