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HIV-1 Gag release from yeast reveals ESCRT interaction with the Gag N-terminal protein region

The HIV-1 protein Gag assembles at the plasma membrane and drives virion budding, assisted by the cellular endosomal complex required for transport (ESCRT) proteins. Two ESCRT proteins, TSG101 and ALIX, bind to the Gag C-terminal p6 peptide. TSG101 binding is important for efficient HIV-1 release, b...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Meusser, Birgit, Purfuerst, Bettina, Luft, Friedrich C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939435/
https://ncbi.nlm.nih.gov/pubmed/32994219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014710
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