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Therapeutic targeting of pancreatic cancer stem cells by dexamethasone modulation of the MKP-1–JNK axis

Postoperative recurrence from microscopic residual disease must be prevented to cure intractable cancers, including pancreatic cancer. Key to this goal is the elimination of cancer stem cells (CSCs) endowed with tumor-initiating capacity and drug resistance. However, current therapeutic strategies c...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Suzuki, Shuhei, Okada, Masashi, Sanomachi, Tomomi, Togashi, Keita, Seino, Shizuka, Sato, Atsushi, Yamamoto, Masahiro, Kitanaka, Chifumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939393/
https://ncbi.nlm.nih.gov/pubmed/33115754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015223
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