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Therapeutic targeting of pancreatic cancer stem cells by dexamethasone modulation of the MKP-1–JNK axis

Postoperative recurrence from microscopic residual disease must be prevented to cure intractable cancers, including pancreatic cancer. Key to this goal is the elimination of cancer stem cells (CSCs) endowed with tumor-initiating capacity and drug resistance. However, current therapeutic strategies c...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Suzuki, Shuhei, Okada, Masashi, Sanomachi, Tomomi, Togashi, Keita, Seino, Shizuka, Sato, Atsushi, Yamamoto, Masahiro, Kitanaka, Chifumi
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939393/
https://ncbi.nlm.nih.gov/pubmed/33115754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015223
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