Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial

PURPOSE: To quantify potential heterogeneity of treatment effect (HTE), of early sedation with dexmedetomidine (DEX) compared with usual care, and identify patients who have a high probability of lower or higher 90-day mortality according to age, and other identified clusters. METHODS: Bayesian anal...

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Detalhes bibliográficos
Publicado no:Intensive Care Med
Main Authors: Shehabi, Yahya, Serpa Neto, Ary, Howe, Belinda D., Bellomo, Rinaldo, Arabi, Yaseen M., Bailey, Michael, Bass, Frances E., Kadiman, Suhaini Bin, McArthur, Colin J., Reade, Michael C., Seppelt, Ian M., Takala, Jukka, Wise, Matt P., Webb, Steve A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
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Original
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939103/
https://ncbi.nlm.nih.gov/pubmed/33686482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-021-06356-8
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