Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial

PURPOSE: To quantify potential heterogeneity of treatment effect (HTE), of early sedation with dexmedetomidine (DEX) compared with usual care, and identify patients who have a high probability of lower or higher 90-day mortality according to age, and other identified clusters. METHODS: Bayesian anal...

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Vydáno v:Intensive Care Med
Hlavní autoři: Shehabi, Yahya, Serpa Neto, Ary, Howe, Belinda D., Bellomo, Rinaldo, Arabi, Yaseen M., Bailey, Michael, Bass, Frances E., Kadiman, Suhaini Bin, McArthur, Colin J., Reade, Michael C., Seppelt, Ian M., Takala, Jukka, Wise, Matt P., Webb, Steve A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2021
Témata:
Original
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939103/
https://ncbi.nlm.nih.gov/pubmed/33686482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-021-06356-8
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