The effect of dexmedetomidine on vasopressor requirements in patients with septic shock: a subgroup analysis of the Sedation Practice in Intensive Care Evaluation [SPICE III] Trial

BACKGROUND: Septic shock is associated with decreased vasopressor responsiveness. Experimental data suggest that central alpha2-agonists like dexmedetomidine (DEX) increase vasopressor responsiveness and reduce catecholamine requirements in septic shock. However, DEX may also cause hypotension and b...

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Bibliografiske detaljer
Udgivet i:Crit Care
Main Authors: Cioccari, Luca, Luethi, Nora, Bailey, Michael, Shehabi, Yahya, Howe, Belinda, Messmer, Anna S., Proimos, Helena K., Peck, Leah, Young, Helen, Eastwood, Glenn M., Merz, Tobias M., Takala, Jukka, Jakob, Stephan M., Bellomo, Rinaldo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367420/
https://ncbi.nlm.nih.gov/pubmed/32678054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-020-03115-x
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