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IgG Epitopes Processed and Presented by IgG(+) B Cells Induce Suppression by Human Thymic-Derived Regulatory T Cells

We described a human regulatory T cell (Treg) population activated by IgG(+) B cells presenting peptides of the heavy C region (Fc) via processing of the surface IgG underlying a model for B cell–Treg cooperation in the human immune regulation. Functionally, Treg inhibited the polarization of naive...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Hsieh, Li-En, Sidney, John, Burns, Jane C., Boyle, David L., Firestein, Gary S., Altman, Yoav, Sette, Alessandro, Franco, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939040/
https://ncbi.nlm.nih.gov/pubmed/33579724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2001009
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