Molecular Mechanisms of Leukocyte Migration and Its Potential Targeting—Lessons Learned From MKL1/SRF-Related Primary Immunodeficiency Diseases

Megakaryoblastic leukemia 1 (MKL1) deficiency is one of the most recently discovered primary immunodeficiencies (PIDs) caused by cytoskeletal abnormalities. These immunological “actinopathies” primarily affect hematopoietic cells, resulting in defects in both the innate immune system (phagocyte defe...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Sprenkeler, Evelien G. G., Guenther, Carla, Faisal, Imrul, Kuijpers, Taco W., Fagerholm, Susanna C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938309/
https://ncbi.nlm.nih.gov/pubmed/33692789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.615477
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