Molecular Mechanisms of Leukocyte Migration and Its Potential Targeting—Lessons Learned From MKL1/SRF-Related Primary Immunodeficiency Diseases

Megakaryoblastic leukemia 1 (MKL1) deficiency is one of the most recently discovered primary immunodeficiencies (PIDs) caused by cytoskeletal abnormalities. These immunological “actinopathies” primarily affect hematopoietic cells, resulting in defects in both the innate immune system (phagocyte defe...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Sprenkeler, Evelien G. G., Guenther, Carla, Faisal, Imrul, Kuijpers, Taco W., Fagerholm, Susanna C.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938309/
https://ncbi.nlm.nih.gov/pubmed/33692789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.615477
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