Molecular Mechanisms of Leukocyte Migration and Its Potential Targeting—Lessons Learned From MKL1/SRF-Related Primary Immunodeficiency Diseases

Megakaryoblastic leukemia 1 (MKL1) deficiency is one of the most recently discovered primary immunodeficiencies (PIDs) caused by cytoskeletal abnormalities. These immunological “actinopathies” primarily affect hematopoietic cells, resulting in defects in both the innate immune system (phagocyte defe...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Sprenkeler, Evelien G. G., Guenther, Carla, Faisal, Imrul, Kuijpers, Taco W., Fagerholm, Susanna C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938309/
https://ncbi.nlm.nih.gov/pubmed/33692789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.615477
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