Increased co-expression of PSMA2 and GLP-1 receptor in cervical cancer models in type 2 diabetes attenuated by Exendin-4: A translational case-control study

BACKGROUND: Type 2 diabetes (T2D) increases the risk of many types of cancer. Dysregulation of proteasome-related protein degradation leads to tumorigenesis, while Exendin-4, a glucagon-like peptide 1 receptor (GLP-1R) agonist, possesses anti-cancer effects. METHODS: We explored the co-expression of...

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Vydáno v:EBioMedicine
Hlavní autoři: Mao, Dandan, Cao, Huanyi, Shi, Mai, Wang, Chi Chiu, Kwong, Joseph, Li, Joshua Jing Xi, Hou, Yong, Ming, Xing, Lee, Heung Man, Tian, Xiao Yu, Wong, Chun Kwok, Chow, Elaine, Kong, Alice Pik Shan, Lui, Vivian Wai Yan, Chan, Paul Kay Sheung, Chan, Juliana Chung Ngor
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938253/
https://ncbi.nlm.nih.gov/pubmed/33684886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103242
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