Increased co-expression of PSMA2 and GLP-1 receptor in cervical cancer models in type 2 diabetes attenuated by Exendin-4: A translational case-control study

BACKGROUND: Type 2 diabetes (T2D) increases the risk of many types of cancer. Dysregulation of proteasome-related protein degradation leads to tumorigenesis, while Exendin-4, a glucagon-like peptide 1 receptor (GLP-1R) agonist, possesses anti-cancer effects. METHODS: We explored the co-expression of...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Mao, Dandan, Cao, Huanyi, Shi, Mai, Wang, Chi Chiu, Kwong, Joseph, Li, Joshua Jing Xi, Hou, Yong, Ming, Xing, Lee, Heung Man, Tian, Xiao Yu, Wong, Chun Kwok, Chow, Elaine, Kong, Alice Pik Shan, Lui, Vivian Wai Yan, Chan, Paul Kay Sheung, Chan, Juliana Chung Ngor
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938253/
https://ncbi.nlm.nih.gov/pubmed/33684886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103242
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