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Establishment and Characterization of an Irinotecan-Resistant Human Colon Cancer Cell Line

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Irinotecan is widely used as a chemotherapeutic drug to treat CRC. However, the mechanisms of acquired resistance to irinotecan in CRC remain inconclusive. In the present study, we established a novel irinotecan-resistant...

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書目詳細資料
發表在:Front Oncol
Main Authors: Wu, Zhuo-Xun, Yang, Yuqi, Zeng, Leli, Patel, Harsh, Bo, Letao, Lin, Lusheng, Chen, Zhe-Sheng
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937870/
https://ncbi.nlm.nih.gov/pubmed/33692943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.624954
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