Sapitinib Reverses Anticancer Drug Resistance in Colon Cancer Cells Overexpressing the ABCB1 Transporter

The efficacy of anti-cancer drugs in patients can be attenuated by the development of multi-drug resistance (MDR) due to ATP-binding cassette (ABC) transporters overexpression. In this in vitro study, we determined the reversal efficacy of the epidermal growth factor receptor (EFGR) inhibitor, sapti...

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Veröffentlicht in:Front Oncol
Hauptverfasser: Gao, Hai-Ling, Gupta, Pranav, Cui, Qingbin, Ashar, Yunali V., Wu, Zhuo-Xun, Zeng, Leli, Lei, Zi-Ning, Teng, Qiu-Xu, Ashby, Charles R., Guan, Yingjun, Chen, Zhe-Sheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581728/
https://ncbi.nlm.nih.gov/pubmed/33163405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.574861
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