Aptamer Functionalized Upconversion Nanotheranostic Agent With Nuclear Targeting as the Highly Localized Drug-Delivery System of Doxorubicin

As a widely used anticancer drug, doxorubicin (DOX) could induce cell death mainly via interfering with DNA activity; thus, DOX could perform therapeutic effects mainly in the cell nucleus. However, most of the reported drug delivery systems lacked the well localization in the nucleus and released D...

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Bibliografiske detaljer
Udgivet i:Front Bioeng Biotechnol
Main Authors: Song, Xinyue, Yan, Tao, Tian, Feng, Li, Fengyan, Ren, Linlin, Li, Qiong, Zhang, Shusheng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Bioengineering and Biotechnology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937813/
https://ncbi.nlm.nih.gov/pubmed/33692990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.639487
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