Aptamer Functionalized Upconversion Nanotheranostic Agent With Nuclear Targeting as the Highly Localized Drug-Delivery System of Doxorubicin

As a widely used anticancer drug, doxorubicin (DOX) could induce cell death mainly via interfering with DNA activity; thus, DOX could perform therapeutic effects mainly in the cell nucleus. However, most of the reported drug delivery systems lacked the well localization in the nucleus and released D...

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Bibliografische gegevens
Gepubliceerd in:Front Bioeng Biotechnol
Hoofdauteurs: Song, Xinyue, Yan, Tao, Tian, Feng, Li, Fengyan, Ren, Linlin, Li, Qiong, Zhang, Shusheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Bioengineering and Biotechnology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937813/
https://ncbi.nlm.nih.gov/pubmed/33692990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.639487
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