Wird geladen...
Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death
Receptor-interacting protein 1 (RIP1; RIPK1) is a key regulator of multiple signaling pathways that mediate inflammatory responses and cell death. TNF-TNFR1 triggered signaling complex formation, subsequent NF-κB and MAPK activation and induction of cell death involve RIPK1 ubiquitination at several...
Gespeichert in:
| Veröffentlicht in: | Cell Death Differ |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7937686/ https://ncbi.nlm.nih.gov/pubmed/32999468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00629-3 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|