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Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death
Receptor-interacting protein 1 (RIP1; RIPK1) is a key regulator of multiple signaling pathways that mediate inflammatory responses and cell death. TNF-TNFR1 triggered signaling complex formation, subsequent NF-κB and MAPK activation and induction of cell death involve RIPK1 ubiquitination at several...
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| 出版年: | Cell Death Differ |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7937686/ https://ncbi.nlm.nih.gov/pubmed/32999468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00629-3 |
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