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TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication

Telomeres are transcribed into telomeric RNA termed as TERRA. However, the transcription itself and excessive TERRA may interfere with telomere replication during S phase. The mechanism that coordinates telomere transcription and replication is unknown. Here, we report that TCOF1 leaves the nucleolu...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Differ
Asıl Yazarlar: Nie, Xin, Xiao, Danqing, Ge, Yuanlong, Xie, Yujie, Zhou, Haoxian, Zheng, Tian, Li, Xiaocui, Liu, Haiying, Huang, Hui, Zhao, Yong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937677/
https://ncbi.nlm.nih.gov/pubmed/33082515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00637-3
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