TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication

Telomeres are transcribed into telomeric RNA termed as TERRA. However, the transcription itself and excessive TERRA may interfere with telomere replication during S phase. The mechanism that coordinates telomere transcription and replication is unknown. Here, we report that TCOF1 leaves the nucleolu...

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I publikationen:Cell Death Differ
Huvudupphovsmän: Nie, Xin, Xiao, Danqing, Ge, Yuanlong, Xie, Yujie, Zhou, Haoxian, Zheng, Tian, Li, Xiaocui, Liu, Haiying, Huang, Hui, Zhao, Yong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937677/
https://ncbi.nlm.nih.gov/pubmed/33082515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00637-3
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