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Arginine Forks are a Widespread Motif to Recognize Phosphate Backbones and Guanine Nucleobases in the RNA Major Groove

RNA recognition by proteins is central to biology. Here we demonstrate the existence of a recurrent structural motif, the ‘arginine fork’, that codifies arginine readout of cognate backbone and guanine nucleobase interactions in a variety of protein-RNA complexes derived from viruses, metabolic enzy...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Chavali, Sai Shashank, Cavender, Chapin E., Mathews, David H., Wedekind, Joseph E
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937406/
https://ncbi.nlm.nih.gov/pubmed/33170672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c09689
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