The effect of spike mutations on SARS-CoV-2 neutralization

Multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines show protective efficacy, which is most likely mediated by neutralizing antibodies recognizing the viral entry protein, spike. Because new SARS-CoV-2 variants are emerging rapidly, as exemplified by the B.1.1.7, B.1.351,...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Rees-Spear, Chloe, Muir, Luke, Griffith, Sarah A., Heaney, Judith, Aldon, Yoann, Snitselaar, Jonne L., Thomas, Peter, Graham, Carl, Seow, Jeffrey, Lee, Nayung, Rosa, Annachiara, Roustan, Chloe, Houlihan, Catherine F., Sanders, Rogier W., Gupta, Ravindra K., Cherepanov, Peter, Stauss, Hans J., Nastouli, Eleni, Doores, Katie J., van Gils, Marit J., McCoy, Laura E.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2021
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936541/
https://ncbi.nlm.nih.gov/pubmed/33713594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108890
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