The zebrafish grime mutant uncovers an evolutionarily conserved role for Tmem161b in the control of cardiac rhythm

The establishment of cardiac function in the developing embryo is essential to ensure blood flow and, therefore, growth and survival of the animal. The molecular mechanisms controlling normal cardiac rhythm remain to be fully elucidated. From a forward genetic screen, we identified a unique mutant,...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Koopman, Charlotte D., De Angelis, Jessica, Iyer, Swati P., Verkerk, Arie O., Da Silva, Jason, Berecki, Geza, Jeanes, Angela, Baillie, Gregory J., Paterson, Scott, Uribe, Veronica, Ehrlich, Ophelia V., Robinson, Samuel D., Garric, Laurence, Petrou, Steven, Simons, Cas, Vetter, Irina, Hogan, Benjamin M., de Boer, Teun P., Bakkers, Jeroen, Smith, Kelly A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936323/
https://ncbi.nlm.nih.gov/pubmed/33597309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018220118
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