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Ppp1r3d deficiency preferentially inhibits neuronal and cardiac Lafora body formation in a mouse model of the fatal epilepsy Lafora disease

Mammalian glycogen chain lengths are subject to complex regulation, including by seven proteins (protein phosphatase-1 regulatory subunit 3, PPP1R3A through PPP1R3G) that target protein phosphatase-1 (PP1) to glycogen to activate the glycogen chain-elongating enzyme glycogen synthase and inactivate...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurochem
Hauptverfasser: Israelian, Lori, Nitschke, Silvia, Wang, Peixiang, Zhao, Xiaochu, Perri, Ami M., Lee, Jennifer P.Y., Verhalen, Brandy, Nitschke, Felix, Minassian, Berge A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936008/
https://ncbi.nlm.nih.gov/pubmed/32892347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.15176
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