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Lafora Disease: A Review of Molecular Mechanisms and Pathology

Lafora’s disease is a neurodegenerative disorder caused by recessive loss-of-function mutations in the EPM2A (laforin glycogen phosphatase) or EPM2B (malin E3 ubiquitin ligase) genes. Neuropathology is characterized by malformed precipitated glycogen aggregates termed Lafora bodies. Asymptomatic unt...

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Bibliografski detalji
Izdano u:Neuropediatrics
Glavni autori: Verhalen, Brandy, Arnold, Susan, Minassian, Berge A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748624/
https://ncbi.nlm.nih.gov/pubmed/30336494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1675238
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