Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques

The establishment of a long-lived viral reservoir is the key obstacle for achieving an HIV-1 cure. However, the anatomic, virologic, and immunologic features of the viral reservoir in tissues during antiretroviral therapy (ART) remain poorly understood. Here we present a comprehensive necroscopic an...

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izdano v:Nat Commun
Main Authors: Cadena, Anthony M., Ventura, John D., Abbink, Peter, Borducchi, Erica N., Tuyishime, Hubert, Mercado, Noe B., Walker-Sperling, Victoria, Siamatu, Mazuba, Liu, Po-Ting, Chandrashekar, Abishek, Nkolola, Joseph P., McMahan, Katherine, Kordana, Nicole, Hamza, Venous, Bondzie, Esther A., Fray, Emily, Kumar, Mithra, Fischinger, Stephanie, Shin, Sally A., Lewis, Mark G., Siliciano, Robert F., Alter, Galit, Barouch, Dan H.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935896/
https://ncbi.nlm.nih.gov/pubmed/33674572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21724-0
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