The Landscape of Persistent Viral Genomes in ART Treated SIV, SHIV, and HIV-2 Infections

Evaluation of HIV cure strategies is complicated by defective proviruses that persist in ART treated patients but are irrelevant to cure. Nonhuman primates (NHP) are essential for testing cure strategies. However, the persisting proviral landscape in ART treated NHPs is uncharacterized. Here we desc...

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Veröffentlicht in:Cell Host Microbe
Hauptverfasser: Bender, Alexandra M., Simonetti, Francesco R., Kumar, Mithra R., Fray, Emily J., Bruner, Katherine M., Timmons, Andrew E., Tai, Katherine Y., Jenike, Katharine M., Antar, Annukka A.R., Liu, Po-Ting, Ho, Ya-Chi, Raugi, Dana N., Seydi, Moussa, Gottlieb, Geoffrey S., Okoye, Afam A., Del Prete, Gregory Q., Picker, Louis J., Mankowski, Joseph L., Lifson, Jeffrey D., Siliciano, Janet D., Laird, Greg. M., Barouch, Dan H., Clements, Janice E., Siliciano, Robert F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724192/
https://ncbi.nlm.nih.gov/pubmed/31295427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.06.005
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