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Optimal sampling strategies for darunavir and external validation of the underlying population pharmacokinetic model

PURPOSE: A variety of diagnostic methods are available to validate the performance of population pharmacokinetic models. Internal validation, which applies these methods to the model building dataset and to additional data generated through Monte Carlo simulations, is often sufficient, but external...

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Detalhes bibliográficos
Publicado no:Eur J Clin Pharmacol
Main Authors: Stillemans, Gabriel, Belkhir, Leila, Vandercam, Bernard, Vincent, Anne, Haufroid, Vincent, Elens, Laure
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935830/
https://ncbi.nlm.nih.gov/pubmed/33175180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-020-03036-2
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