RADX controls RAD51 filament dynamics to regulate replication fork stability

The RAD51 recombinase forms nucleoprotein filaments to promote double-strand break repair, replication fork reversal, and fork stabilization. The stability of these filaments is highly regulated since both too little and too much RAD51 activity can cause genome instability. RADX is a single-strand D...

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Publicado en:Mol Cell
Main Authors: Adolph, Madison B., Mohamed, Taha M., Balakrishnan, Swati, Xue, Chaoyou, Morati, Florian, Modesti, Mauro, Greene, Eric C., Chazin, Walter J., Cortez, David
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935748/
https://ncbi.nlm.nih.gov/pubmed/33453169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.12.036
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