RADX controls RAD51 filament dynamics to regulate replication fork stability

The RAD51 recombinase forms nucleoprotein filaments to promote double-strand break repair, replication fork reversal, and fork stabilization. The stability of these filaments is highly regulated since both too little and too much RAD51 activity can cause genome instability. RADX is a single-strand D...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Adolph, Madison B., Mohamed, Taha M., Balakrishnan, Swati, Xue, Chaoyou, Morati, Florian, Modesti, Mauro, Greene, Eric C., Chazin, Walter J., Cortez, David
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935748/
https://ncbi.nlm.nih.gov/pubmed/33453169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.12.036
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