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Immune Regulation of the cGAS-STING Signaling Pathway in the Tumor Microenvironment and Its Clinical Application

As a DNA receptor in the cytoplasm, cyclic GMP-AMP synthase (cGAS) contributes to the recognition of abnormal DNA in the cytoplasm and contributes to the stimulator of interferon genes (STING) signaling pathway. cGAS could mediate the expression of interferon-related genes, inflammatory-related fact...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Pu, Feifei, Chen, Fengxia, Liu, Jianxiang, Zhang, Zhicai, Shao, Zengwu
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935450/
https://ncbi.nlm.nih.gov/pubmed/33688199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S298958
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