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Immune Regulation of the cGAS-STING Signaling Pathway in the Tumor Microenvironment and Its Clinical Application

As a DNA receptor in the cytoplasm, cyclic GMP-AMP synthase (cGAS) contributes to the recognition of abnormal DNA in the cytoplasm and contributes to the stimulator of interferon genes (STING) signaling pathway. cGAS could mediate the expression of interferon-related genes, inflammatory-related fact...

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Publicado en:Onco Targets Ther
Main Authors: Pu, Feifei, Chen, Fengxia, Liu, Jianxiang, Zhang, Zhicai, Shao, Zengwu
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935450/
https://ncbi.nlm.nih.gov/pubmed/33688199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S298958
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