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Immune Regulation of the cGAS-STING Signaling Pathway in the Tumor Microenvironment and Its Clinical Application

As a DNA receptor in the cytoplasm, cyclic GMP-AMP synthase (cGAS) contributes to the recognition of abnormal DNA in the cytoplasm and contributes to the stimulator of interferon genes (STING) signaling pathway. cGAS could mediate the expression of interferon-related genes, inflammatory-related fact...

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發表在:Onco Targets Ther
Main Authors: Pu, Feifei, Chen, Fengxia, Liu, Jianxiang, Zhang, Zhicai, Shao, Zengwu
格式: Artigo
語言:Inglês
出版: Dove 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935450/
https://ncbi.nlm.nih.gov/pubmed/33688199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S298958
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